F-SECURE ANTI-VIRUS FOR MICROSOFT EXCHANGE 6.62 - Administrator's Manual - page 384
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Q. A message is not scanned if it comes from a trusted mailbox.
Why?
A. If an infected attachment arrives to a mailbox, it passes the virus
scanner but it is not disinfected or stopped. The real-time scanner
scans messages in the message store only once, so when the
infected message is sent from the trusted mailbox to another mailbox
inside the same message store, the real-time scanner does not scan
it again.
If you use trusted mailboxes, store those messages in a different
message store. When a message moves between message stores, it
is scanned and infected attachments can be disinfected. You can also
run the manual scan periodically to remove infected attachments.
Q. When I release an e-mail from the Quarantine, sometimes two
warning messages are sent to the recipient. Why?
A. When you release an e-mail that has an infected attachment from the
Quarantine and the user uses POP3 to retrieve mail from the server,
the user may receive two warning messages while the infected
attachment remains in the Quarantine.
Local Protection with F-Secure Anti-Virus for Windows Servers
Q. Can all files on a Microsoft Exchange computer be scanned for
viruses, or are some files and folders excluded from scanning
automatically?
A. The working and quarantine directories of F-Secure Anti-Virus for
Microsoft Exchange are added to the OAS excluded list during the
installation.
Microsoft Knowledgebase article #245822 ‘Recommendations for
troubleshooting an Exchange computer with antivirus software
installed’ describes what files and folders should never be scanned
with file-based antivirus software: