Abbott i-STAT 1 System Manual - page 531
Rev. Date: 23-May-12
Art: 716969-00J
BNP - 13
Interference Testing
The following substances were found to have no significant effect (less than 10%) on the BNP method,
when added to a plasma pool containing approximately 1000 pg/mL of B-type natriuretic peptide at the
concentrations indicated:
Interference studies were based on CLSI guideline EP7-A.
36
Compound
Test Level
(μmol/L unless otherwise indicated)
Acetaminophen
1660
Allopurinol
294
Ampicillin
152
Ascorbic Acid
227
Acetyl Salicylic Acid
3330
Atenolol
37.6
Caffeine
308
Captopril
23
Chloramphenicol
155
Diclofenac
169
Digoxin
6.15
Dopamine
5.87
Enalaprilat
0.86
Erythromycin
81.6
Furosemide
181
Sodium Heparin
90 U/mL
Ibuprofen
2425
Isosorbide dinitrate
636
Methyldopa
71
Nicotine
6.2
Nifedipine
1156
Phenytoin
198
Propanolol
7.71
Salicylic Acid
4340
Theophylline
222
Verapamil
4.4
Warfarin
64.9